Unıversity Of Illinois, College Of Pharmacy, USA
Dr. Jeremy Johnson, associate professor of pharmacy practice at the University of Illinois at Chicago College of Pharmacy and Leader of pre-clinical studies and pharmacokinetics for UICentre (the University of Illinois Collaborative Engagement of Therapeutic Research Enterprise), will present his studies on the disruption of androgen receptor with phytochemicals from the mangosteen fruit and Mediterranean herb rosemary.
During his presentation he will highlight phytochemicals that can disrupt androgen receptor function while promoting degradation of the androgen receptor. Additional studies will describe the role of targeting splice variants known to cause resistance to anti-androgens during prostate cancer treatment. Finally, in vivo studies will describe the pharmacokinetic and efficacy of selected agents to provide a perspective on the future development of selective androgen receptor degradation enhancers for prostate cancer.